Adenine nucleotide translocator (ANT)

腺嘌呤核苷酸转运蛋白

英文解释

Adenine nucleotide translocator (ANT) is a family of proteins involved in cell death pathways. ANT exchanges ATP with ADP? between the intermembrane space to the matrix, and trigger the process of mitochondrial membrane permeabilization, which leads irreversibly to cell death.

中文解释

腺嘌呤核苷酸转运蛋白 (ANT) 是一个参与细胞死亡途径的蛋白质家族。ANT 在线粒体膜间隙与基质之间交换 ATP 和 AD P，触发线粒体膜透化过程，且可导致细胞不可逆的死亡。

参考文献

[1]. Brenner C, et al. Adenine nucleotide translocase family: four isoforms for apoptosis modulation in cancer. Oncogene. 2011 Feb 24;30(8):883-95.