AMP-activated protein kinase (AMPK)

AMP 活化蛋白激酶

英文解释

AMP-activated protein kinase (AMPK) is an enzyme which is a highly conserved sensor of low intracellular ATP levels. AMPK is a central mediator of the cellular response to energetic stress and mitochondrial insults and coordinates multiple features of autophagy and mitochondrial biology.

中文解释

AMP 活化蛋白激酶 (AMPK) 是一种酶，它是低细胞内 ATP 水平的高度保守传感器。AMPK 是细胞对能量应激和线粒体损伤的反应的中心介质，并协调自噬和线粒体生物学的多种特征。

参考文献

[1]. Herzig S, et al. AMPK: guardian of metabolism and mitochondrial homeostasis. Nat Rev Mol Cell Biol. 2018 Feb;19(2):121-135.