ATP binding cassette (ABC)

ATP 结合盒

英文解释

ATP-binding cassette (ABC) transporter superfamily is one of the largest membrane protein families existing in wide spectrum of organisms from prokaryotes to human. ABC transporters are also known as efflux pumps because they mediate the cross-membrane transportation of various endo- and xenobiotic molecules energized by ATP hydrolysis.

中文解释

ATP 结合盒 (ABC) 转运蛋白家族是存在于从原核生物到人类的广泛生物中的最大的膜蛋白家族之一。ABC 转运蛋白也被称为外排泵，因为它们介导由 ATP 水解激发的各种内、外生物分子的跨膜运输。

参考文献

[1]. Wang JQ, et al. ATP-binding cassette (ABC) transporters in cancer: A review of recent updates. J Evid Based Med. 2021 Sep;14(3):232-256.