Autophagosome

自噬体

英文解释

Autophagosomes are double-membrane vesicles newly formed during autophagy to engulf a wide range of intracellular material and transport this autophagic cargo to lysosomes (or vacuoles in yeasts and plants) for subsequent degradation. Autophagosome biogenesis responds to a plethora of signals and involves unique and dynamic membrane processes.

中文解释

自噬体是在自噬过程中新形成的双膜囊泡，可吞噬大量细胞内物质，并将这种自噬货物运输到溶酶体 (或酵母和植物中的液泡) 进行随后的降解。自噬体的生物发生响应过多的信号，并涉及独特的和动态的膜过程。

参考文献

[1]. Nakatogawa H. Mechanisms governing autophagosome biogenesis. Nat Rev Mol Cell Biol. 2020 Aug;21(8):439-458.