B-cell receptor (BCR)

B 细胞受体

英文解释

B-cell receptor (BCR) is essential for normal B-cell development and maturation. In an increasing number of B-cell malignancies, BCR signaling is implicated as a pivotal pathway in tumorigenesis.

中文解释

B 细胞受体 (BCR) 是 B 细胞正常发育和成熟所必需的。在越来越多的 B 细胞恶性肿瘤中，BCR 信号通路被认为是肿瘤发生的关键途径。

参考文献

[1]. Niemann CU, et al. B-cell receptor signaling as a driver of lymphoma development and evolution. Semin Cancer Biol. 2013 Dec;23(6):410-21.