Calcineurin (CaN)

钙调磷酸酶

英文解释

Calcineurin (CaN) is a eukaryotic Ca2+- and calmodulin-dependent serine/threonine protein phosphatase. It is a heterodimeric protein consisting of a catalytic subunit calcineurin A, which contains an active site dinuclear metal center, and a tightly associated, myristoylated, Ca2+-binding subunit, calcineurin B.

中文解释

钙调磷酸酶 (CaN) 是一种真核 Ca2+ 和钙调蛋白依赖性丝氨酸/苏氨酸蛋白磷酸酶。它是一种异二聚体蛋白，由催化亚基钙调神经磷酸酶 A 和紧密结合的豆蔻酰化 Ca2+ 结合亚基钙调神经磷酸酶 B 组成，后者含有活性位点双核金属中心。

参考文献

[1]. F Rusnak, et al. Calcineurin: form and function. Physiol Rev. 2000 Oct;80(4):1483-521.