cAMP-dependent protein kinase A (PKA)

cAMP 依赖性蛋白激酶 A

英文解释

cAMP-dependent protein kinase A (PKA) is an enzyme that modulates Hh signaling activity through phosphorylating the transcription factor Cubitus interruptus (Ci) and G protein coupled receptor (GPCR) family protein Smoothened (Smo).

中文解释

cAMP 依赖性蛋白激酶 A (PKA) 是一种通过磷酸化转录因子 Cubitus interruptus (Ci) 和 G 蛋白偶联受体 (GPCR) 家族 Smoothened (Smo) 来调节 Hh 信号通路活性的酶。

参考文献

[1]. Chen P, et al. Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A. Sci Rep. 2017 Jun 6;7(1):2891.