Chaperone-mediated autophagy (CMA)

伴侣介导的自噬

英文解释

Chaperone-mediated autophagy (CMA) is one of the proteolytic systems that contributes to degradation of intracellular proteins in lysosomes. In the process of CMA, the proteins undergo degradation by this autophagic pathway are selected individually through a recognition motif in their amino acid sequences.

中文解释

伴侣介导的自噬 (CMA) 是一种蛋白水解系统，有助于溶酶体中细胞内蛋白质的降解。在 CMA 过程中，通过这种途径降解的蛋白可通过其氨基酸序列中的识别基序而被选择性降解。

参考文献

[1]. Cuervo AM, et al. Chaperone-mediated autophagy: roles in disease and aging. Cell Res. 2014 Jan;24(1):92-104.