Chemokines

趋化因子

英文解释

Chemokines are a large family of small, secreted proteins that signal through cell surface G protein-coupled heptahelical chemokine receptors. Chemokines are important in the development and homeostasis of the immune system, and are involved in all protective or destructive immune and inflammatory responses.

中文解释

趋化因子是一大类小型分泌蛋白，通过细胞表面 G 蛋白偶联的七螺旋趋化因子受体进行信号传导。趋化因子在免疫系统的发育和稳态中很重要，并且参与所有保护性或破坏性免疫和炎症反应。

参考文献

[1]. Hughes CE, et al. A guide to chemokines and their receptors. FEBS J. 2018 Aug;285(16):2944-2971.