Covalent inhibitor

共价抑制剂

英文解释

Covalent inhibitor is a kind of compound that can form a covalent bond with a specific target.Covalent inhibitors increases the duration of interaction with its target, and thereby avoiding off-target toxicity.

中文解释

共价抑制剂是一种能与特定靶点形成共价键的化合物。共价抑制剂增加了与其靶点相互作用的持续时间，从而避免了脱靶毒性。

参考文献

[1]. CovalSutanto F,et al. Covalent inhibitors: a rational approach to drug discovery. RSC Med Chem. 2020 Jul 2;11(8):876-884. ent inhibitors: a rational approach to drug discovery.