Cysteine proteases (CPs)

半胱氨酸蛋白酶

英文解释

Cysteine proteases (CPs) are proteins with molecular mass about 21–30 kDa. CPs play key roles in the pathogenesis of protozoan parasites, including cell/tissue penetration, hydrolysis of host or parasite proteins, autophagy, and evasion or modulation of the host immune response.

中文解释

半胱氨酸蛋白酶 (CPs) 是一种分子量约为 21-30 kDa 的蛋白质。CPs 在原生动物寄生虫的发病机制中起着关键作用，包括细胞/组织渗透、宿主或寄生虫蛋白的水解、自噬以及宿主免疫的逃避或调节响应。

参考文献

[1]. Z Grzonka, et al. Structural studies of cysteine proteases and their inhibitors. Acta Biochim Pol. 2001;48(1):1-20.
[2]. Jair L Siqueira-Neto, et al. Cysteine proteases in protozoan parasites. PLoS Negl Trop Dis. 2018 Aug 23;12(8):e0006512