Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)

细胞毒性 T 淋巴细胞相关蛋白 4

英文解释

Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is one of the essential brakes expressed on T cells that prevent T-cell hyperactivation-associated autoimmune disorders. Several CTLA4 polymorphisms were implicated in the regulation of gene expression.

中文解释

细胞毒性 T 淋巴细胞相关蛋白 4 (CTLA-4) 是 T 细胞上表达的重要抑制因子之一，可预防 T 细胞过度激活相关的自身免疫性疾病。一些 CTLA4 多态性参与了基因表达的调控。

参考文献

[1]. Gouda NS, et al. Impact of cytotoxic T-lymphocyte-associated protein 4 codon 17 variant and expression on vitiligo risk. J Clin Lab Anal. 2021 Jun;35(6):e23777.