DOC-2/DAB2 interacting protein (DAB2IP)

DOC-2/DAB2 相互作用蛋白 (DAB2IP)

英文解释

DOC-2/DAB2 interacting protein (DAB2IP) is a novel tumor suppressor in malignancies. DAB2IP suppresses growth and metastasis of NPC probably by targeting PI3K/Akt pathway, and may act as a hopeful therapeutic target for NPC.

中文解释

DOC-2/DAB2 相互作用蛋白 (DAB2IP) 是恶性肿瘤中的新型肿瘤抑制因子。 DAB2IP可能通过靶向PI3K/Akt通路抑制鼻咽癌的生长和转移，有望成为鼻咽癌的治疗靶点。

参考文献

[1]. Wang B, et al. DOC-2/DAB2 interactive protein regulates proliferation and mobility of nasopharyngeal carcinoma cells by targeting PI3K/Akt pathway. Oncol Rep. 2017 Jul;38(1):317-324.