E-type cyclins/cyclin E
发布时间:2023-03-22 22:08:39
浏览次数:182
E-type cyclins/cyclin E
E 型细胞周期蛋白/细胞周期蛋白 E
英文解释
E-type cyclins/cyclin E, represent key components of the core cell cycle machinery. In mammalian cells, two E-type cyclins, E1 and E2, activate cyclin-dependent kinase 2 (CDK2) and drive cell cycle progression by phosphorylating several cellular proteins.
中文解释
E 型细胞周期蛋白/细胞周期蛋白 E,代表核心细胞周期机制的关键组成部分。在哺乳动物细胞中,两种 E 型细胞周期蛋白 E1 和 E2 激活细胞周期蛋白依赖性激酶 2 (CDK2) 并通过磷酸化几种细胞蛋白来驱动细胞周期进程。
参考文献
[1]. Chen Chu, et al. Cyclin E in normal physiology and disease states. Trends Cell Biol. 2021 Sep;31(9):732-746.