Fibroblast growth factor receptor (FGFR)

成纤维细胞生长因子受体

英文解释

Fibroblast growth factor receptor (FGFR) is a family of receptor tyrosine kinases expressed on the cell membrane. FGFR consists of four members: FGFR1 to FGFR4, and plays crucial roles in both developmental and adult cells. FGFR is a target for the therapy of various cancers.

中文解释

成纤维细胞生长因子受体 (FGFR) 是在细胞膜上表达的受体酪氨酸激酶家族。FGFR 由四个成员组成: FGFR1-FGFR4，在发育细胞和成体细胞中都起着至关重要的作用。FGFR 是治疗各种癌症的靶标。

参考文献

[1]. Dai S, et al. Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors. Cells. 2019 Jun 18;8(6):614.