Filamenting temperature-sensitive mutant Z (FtsZ)

丝状温度敏感性突变体 Z

英文解释

Filamenting temperature-sensitive mutant Z (FtsZ) is a key protein involved in cytokinesis, an important process for Mtb proliferation and viability. FtsZ is required for bacterial cell division because it polymerizes into a structure called the Z-ring, which recruits accessory division proteins to the septum.

中文解释

丝状温度敏感性突变体 Z (Filamenting temperature-sensitive mutant Z, FtsZ) 是参与胞质分裂的关键蛋白，胞质分裂是 Mtb 增殖和活力的重要过程。FtsZ 是细菌细胞分裂所必需的，因为它聚合成一个叫做 z 环的结构，z 环募集辅助分裂蛋白到隔膜。

参考文献

[1]. Lazo EO, et al. Novel T9 loop conformation of filamenting temperature-sensitive mutant Z from Mycobacterium tuberculosis. Acta Crystallogr F Struct Biol Commun. 2019 May 1;75(Pt 5):359-367.