Folate receptor α (FRα)

叶酸受体α

英文解释

Folate receptor α (FRα) is a 38 kDa Glycosylphosphatidylinositol (GPI)-anchored protein that binds folic acid with high affinity and transports folate by receptor-mediated endocytosis.

中文解释

叶酸受体α (FRα) 是一个38 kDa 的糖基磷脂酰肌醇 Glycosylphosphatidylinositol (GPI)-锚定蛋白，具有高亲和力结合叶酸 folic acid，并通过受体介导的内吞作用运输叶酸。

参考文献

[1]. Spannuth WA, et, al. Farletuzumab in epithelial ovarian carcinoma. Expert Opin Biol Ther. 2010 Mar;10(3):431-7.