Guanine nucleotide exchange factor (GEF)

鸟嘌呤核苷酸交换因子

英文解释

Guaninenucleotide-exchangefactors (GEFs) activate the function of guaninenucleotide-binding proteins (G-proteins) by promoting the exchange of GDP for GTP on the latter.

中文解释

鸟嘌呤核苷酸交换因子 (GEFs) 通过促进鸟嘌呤核苷酸结合蛋白（G 蛋白）上 GTP 与 GDP 的交换，从而激活 G 蛋白的功能。

参考文献

[1]. Yusuke Sekine, et al. Fluorescence Intensity-Based eIF2B's Guanine Nucleotide-Exchange Factor Activity Assay. Methods Mol Biol. 2022;2428:187-196.