Hedgehog (Hh) pathway

Hedgehog 信号

英文解释

Hedgehog (Hh) signaling pathway was first identified in the common fruit fly. Hh signaling is a highly conserved evolutionary pathway of signal transmission from the cell membrane to the nucleus. The Hh signaling pathway plays an important role in the embryonic development, which exerts its biological effects through a signaling cascade.

中文解释

Hedgehog (Hh) 信号通路首次在普通果蝇中被发现。Hh 信号是一种从细胞膜到细胞核信号传递的高度保守的进化途径。Hh 信号通路在胚胎发育过程中起着重要作用，它通过信号级联发挥其生物学效应。

参考文献

[1]. Ana Marija Skoda, et al. The role of the Hedgehog signaling pathway in cancer: A comprehensive review. Bosn J Basic Med Sci. 2018 Feb 20;18(1):8-20.