Hepatocyte growth factor (HGF)

肝细胞生长因子

英文解释

Hepatocyte growth factor (HGF), also knownasscatter factor (SF),is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells and T cells. It has been shown to have a major role in embryonic organ development, specifically in myogenesis, in adult organ regeneration, and in wound healing.

中文解释

肝细胞生长因子 (HGF)，也是分散因子 (SF)，是一种旁分泌细胞生长、运动和形态形成因子。它由间充质细胞和靶细胞分泌，主要作用于上皮细胞和内皮细胞，但也作用于造血祖细胞和 T 细胞。它已被证明在胚胎器官发育中，特别是在肌肉形成中，在成人器官再生和伤口愈合中具有重要作用。

参考文献

[1]. Lin XY, et al.
[Role of Hepatocyte Growth Factor in Wound Repair]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2018 Dec 20;40(6):822-826. Chinese.