Human liver microsomes (HLMs)

人肝微粒体

英文解释

Human liver microsomes contain a wide variety of drug-metabolizing enzymes and are commonly used to support in vitro metabolism studies, such as reaction phenotyping, metabolic stability, metabolite identification (MetID), and enzyme inhibition.

中文解释

人肝微粒体 (HLMs) 含有多种药物代谢酶，通常用于支持体外代谢研究，如反应表型、代谢稳定性、代谢物鉴定 (MetID) 和酶抑制。

参考文献

[1]. Asha S, et al. Role of human liver microsomes in in vitro metabolism of drugs-a review. Appl Biochem Biotechnol. 2010 Mar;160(6):1699-722.