Immune checkpoint proteins (ICP)

免疫检查点蛋白

英文解释

Immune checkpoint proteins (ICP) are regulators of immune system. The ICP dysregulation silences the host immune response to cancer-specific antigens, contributing to the occurrence and progress of various cancers.

中文解释

免疫检查点蛋白 (ICP) 是免疫系统的调节因子。ICP 失调抑制了宿主对癌症特异性抗原的免疫反应，促进了各种癌症的发生和发展。

参考文献

[1]. Yang Q, et al. Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins. Cancer Lett. 2018 Sep 1;431:73-84.