Immune-responsive gene 1 ( IRG1)

免疫应答基因 1

英文解释

Immune-responsive gene 1 ( IRG1) is a mitochondrial enzyme that produces itaconate under inflammatory conditions, principally in cells of myeloid lineage.

中文解释

免疫应答基因 1 (Irg1) 是一种线粒体酶，在炎症条件下产生衣康酸盐，主要在髓系细胞中。

参考文献

[1]. Nair S, et al.?Irg1?expression in myeloid cells prevents immunopathology during?M. tuberculosis?infection. J Exp Med. 2018 Apr 2;215(4):1035-1045.