Induced pluripotent stem cells (iPSCs)

诱导多能干细胞

英文解释

Induced pluripotent stem cells (iPSCs)are derived from adult somatic cells by ectopic expression of stem cell factors OCT4, SOX2, MYC and KLF4. iPSCs have characteristic features similar to embryonic stem cells, is a new strategy to model human cancer.

中文解释

诱导多能干细胞 (iPSCs) 是通过干细胞因子 OCT4、SOX2、MYC 和 KLF4 的异位表达从成人体细胞中分化而来的。iPSCs 具有类似于胚胎干细胞的特征，是一种针对人类癌症的新靶点。

参考文献

[1]. Bindhya S, et al. Induced pluripotent stem cells: A new strategy to model human cancer. Int J Biochem Cell Biol. 2019 Feb;107:62-68.