Isocitrate dehydrogenase 1 (IDH1)

异柠檬酸脱氢酶 1

英文解释

Isocitrate dehydrogenase 1 (IDH1) is an enzyme located in the cytoplasm and peroxisomes. IDH1 participates in lipid metabolism and glucose sensing, including catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate.

中文解释

异柠檬酸脱氢酶 1 (IDH1) 是一种位于细胞质和过氧化物酶体中的酶。IDH1 参与脂质代谢和葡萄糖传感，包括催化异柠檬酸氧化脱羧为 2-酮戊二酸。

参考文献

[1]. Hodges TR, et al. Isocitrate dehydrogenase 1: what it means to the neurosurgeon: a review. J Neurosurg. 2013 Jun;118(6):1176-80.