Lysophosphatidyl choline (LPC)
发布时间:2023-03-22 22:08:39
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Lysophosphatidyl choline (LPC)
溶血磷脂酰胆碱
英文解释
Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid generated by pathological activities. LPC is also a major phospholipid component of oxidized low-density lipoprotein (Ox-LDL). LPC plays an important role in atherosclerosis and inflammatory diseases by altering various functions in a number of cell-types, including endothelial cells, smooth muscle cells, monocytes, macrophages, and T-cells.
中文解释
溶血磷脂酰胆碱 (LPC) 是一种由病理活动产生的具有生物活性的促炎脂质。 LPC 也是氧化低密度脂蛋白 (Ox-LDL) 的主要磷脂成分。 LPC 通过改变许多细胞类型(包括内皮细胞、平滑肌细胞、单核细胞、巨噬细胞和 T 细胞)的各种功能,在动脉粥样硬化和炎症性疾病中发挥重要作用。
参考文献
[1]. Takayuki Matsumoto, et al. Role of lysophosphatidylcholine (LPC) in atherosclerosis. Curr Med Chem. 2007;14(30):3209-20.