Monoamine oxidase type A (MAOA)

A 型单胺氧化酶

英文解释

Monoamine oxidase type A (MAOA) is a subform of Monoamine Oxidase. MAOA catabolizes monoamine transmitters, serotonin, norepinephrine and dopamine, and is critical in the onset, progression and therapy of neuropsychiatric disorders. MAOA inhibitors act as antidepressant and antianxiety agents.

中文解释

A 型单胺氧化酶 (MAOA) 是单胺氧化酶的亚型之一。MAOA 分解代谢单胺递质、5-羟色胺、去甲肾上腺素和多巴胺，对神经精神疾病的发生、进展和治疗至关重要。MAOA 抑制剂被用作抗抑郁剂和抗焦虑剂。

参考文献

[1]. Naoi M, et al. Type A monoamine oxidase and serotonin are coordinately involved in depressive disorders: from neurotransmitter imbalance to impaired neurogenesis. J Neural Transm (Vienna). 2018 Jan;125(1):53-66.