Nuclear factor E2-related factor 2 (Nrf2)

核因子 E2 相关因子-2

英文解释

Nuclear factor E2-related Factor-2 (Nrf2), is a key transcription factor that regulates cellular redox homeostasis, has been reported to play both protective and pathogenic roles depending on the disease conditions through undefined mechanism.

中文解释

核因子 E2 相关因子-2 (Nrf2) 是调节细胞氧化还原稳态的关键转录因子，据报道根据疾病情况发挥保护和致病作用，但作用机制尚不明确。

参考文献

[1]. Zhao C, et al. Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation. J Biol Chem. 2014 Jun 13;289(24):17020-9.