Open Field Test

旷场实验

英文解释

The open field test is an experiment used to test the learning and memory ability of mice. It can detect the level of spontaneous activity and anxiety in the animals. It is the most widely used in neuropsychiatric diseases and neuropsychopharmacology. In the experiment, mice were placed in the center of an open cube test box with a side length of 50 cm and a height of 30 cm, and their moving distance, speed, percentage of moving distance in the central area, stay time in the central area, and moving distance of large and small movements were recorded.

中文解释

旷场实验是一种用于测试小鼠学习记忆能力的实验，可检测动物的自发活动和焦虑水平，在神经精神疾病和神经精神药理学中应用最为广泛。实验中，将小鼠放置于边长50 cm，高 30 cm 的立方体开放式试验箱的中心点，记录小鼠的移动距离、速度、在中心区移动距离的百分比、在中心区停留时间、大运动和小运动的移动距离。

参考文献

[1]. Kraeuter AK, et al. The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behavior. Methods Mol Biol. 2019;1916:99-103.