Peptidoglycan

肽聚糖

英文解释

Peptidoglycan is a direct target for innate immune receptors and also regulates the accessibility of other pathogen-associated molecular patterns (PAMPs) to additional innate immune receptors. Subtle structural modifications to peptidoglycan can influence the ability of the innate immune system to detect bacteria and can allow bacteria to evade or alter host defences.

中文解释

肽聚糖 (Peptidoglycan) 是先天免疫受体的直接靶点，调节其他 pathogen-associated molecular patterns (PAMPs) 对其他先天免疫受体的可及性。肽聚糖的细微结构修饰可以影响先天免疫系统检测细菌的能力，并允许细菌逃避或改变宿主的防御。

参考文献

[1]. Wolf AJ, Underhill DM. Peptidoglycan recognition by the innate immune system. Nat Rev Immunol. 2018 Apr;18(4):243-254.