Phosphodiester bond

磷酸二酯键

英文解释

Phosphodiester bond is a chemical group that refers to two ester bonds formed by esterification of one molecule of phosphoric acid with two alcohols (hydroxyl groups). Phosphodiester bond is involved in forming the molecular structure of DNA, and the break of nucleotide phosphodiester bond can lead to DNA degradation.

中文解释

磷酸二酯键是一种化学基团，指一分子磷酸与两个醇 (羟基) 酯化形成的两个酯键。磷酸二酯键参与形成 DNA 的分子结构，核苷酸磷酸二酯键的断裂可导致 DNA 降解。

参考文献

[1]. Tong Y, et al. EGFR induces DNA decomposition via phosphodiester bond cleavage. Sci Rep. 2017 Mar 8;7:43698.