Phospholipase C (PLC)

磷脂酶 C

英文解释

Phospholipase C (PLC) is a key enzyme in phosphoinositide metabolism. PLC hydrolyses phosphatidylinositol 4,5-bis-phosphate to generate two second messengers, inositol 1,4,5-trisphosphate and diacylglycerol, that generate diverse cellular responses.

中文解释

磷脂酶 C (Phospholipase C, PLC) 是磷酸肌醇代谢的关键酶。PLC 水解磷脂酰肌醇 4,5-二磷酸生成两种第二信使，1,4,5-三磷酸肌醇和二酰基甘油，产生不同的细胞反应。

参考文献

[1]. Nakamura Y, Fukami K. Regulation and physiological functions of mammalian phospholipase C. J Biochem. 2017 Apr 1;161(4):315-321.