PI3K/AKT pathway

PI3K/AKT 通路

英文解释

PI3K/AKT pathway is one of the major signal transduction pathways that regulates numerous cellular activities in vivo. The main functions of this pathway include induction of stem cell differentiation and metastasis, promotion of cell proliferation, inhibition of apoptosis, and regulation of tissue inflammation, tumor growth, and invasion.

中文解释

PI3K/AKT 通路 (PI3K/AKT pathway) 是体内调控多种细胞活性的主要信号转导通路之一。该通路的主要作用包括诱导干细胞分化和转移、促进细胞增殖、抑制细胞凋亡、调节组织炎症、肿瘤生长和侵袭。

参考文献

[1]. Wang M, et al. Role of the PI3K/Akt signaling pathway in liver ischemia reperfusion injury: a narrative review. Ann Palliat Med. 2022 Feb;11(2):806-817.