Plasminogen activator inhibitor-1 (PAI-1)

纤溶酶原激活物抑制剂-1

英文解释

Plasminogen activator inhibitor-1 (PAI-1) is a member of serine protease inhibitor (SERPIN) family that acts as the primary inhibitor of two main mammalian plasminogen activators, urinary-type (uPA) and tissue-type (tPA).

中文解释

纤溶酶原激活物抑制剂-1 (PAI-1) 是丝氨酸蛋白酶抑制剂 (SERPIN) 家族的成员，它是两种主要哺乳动物纤溶酶原激活剂尿型 (uPA) 和组织型 (tPA) 的抑制剂。

参考文献

[1]. Gils A, et al. Plasminogen activator inhibitor-1. Curr Med Chem. 2004 Sep;11(17):2323-34.