Progerin

早老素

英文解释

Progerin, a truncated unprocessed lamin A protein, causes tissue aging and degeneration. Progerin can be used for the research of premature aging disorder including Hutchinson-Gilford progeria syndrome (HGPS).

中文解释

早老素是一种截短的未加工核纤层蛋白 A 蛋白，会导致组织老化和退化。早老素可用于早衰症的研究，包括 Hutchinson-Gilford 早衰综合征 (HGPS)。

参考文献

[1]. Xiaolong Xu, et al. Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane. Theranostics. 2019 Apr 12;9(8):2252-2267.