Promoter

启动子

英文解释

Promoter is a short region of DNA (100-1000 bp) where transcription of a gene by RNA polymerase begins. It is typically located directly upstream or at the 5′ end of the transcription initiation site. DNA promoter has been proven to be the primary cause of many human diseases, especially diabetes, cancer, or Huntington's disease.

中文解释

启动子是 DNA 的一个短区域 (100-1000 bp)，RNA 聚合酶在此开始转录基因。它通常位于转录起始位点的上游或 5 ' 端。DNA 启动子已被证明是许多人类疾病的主要原因，特别是糖尿病、癌症或亨廷顿舞蹈症。

参考文献

[1]. Le NQK, et al. Classifying Promoters by Interpreting the Hidden Information of DNA Sequences via Deep Learning and Combination of Continuous FastText N-Grams. Front Bioeng Biotechnol. 2019 Nov 5;7:305.