Proto-oncogenes

原癌基因

英文解释

Proto-oncogenes are normal genes which affect normal cell growth and proliferation, but which have the potential to contribute to cancer development if their expression is altered. A variety of events may activate proto-oncogenes and convert them from benign genes to cancer genes. These events include mutations of nucleic acid sequences, chromosomal rearrangements, and amplification of the number of genes.

中文解释

原癌基因 (Proto-oncogenes) 是影响正常细胞生长和增殖的正常基因，但如果它们的表达发生改变，就有可能促进癌症的发展。多种事件可能激活原癌基因，并将其从良性基因转化为癌症基因。这些事件包括核酸序列突变、染色体重排和基因数量的扩增。

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