Restriction enzymes

限制性核酸内切酶

英文解释

Restriction endonuclease is a class of enzymes that can recognize a specific nucleotide sequence and cut the phosphodiester bond between two deoxyribonucleotides, abbreviated as restriction enzyme. There are three types of restriction enzymes, which catalyze the hydrolysis of host DNA methylation and unmethylated DNA; Catalytic hydrolysis of unmethylated DNA; Or exercise the role of modification and cognitive cutting.

中文解释

限制性核酸内切酶是能够识别特定核苷酸序列，并切割两个脱氧核糖核苷酸之间磷酸二酯键的一类酶，简称限制酶。限制酶具有三种类型，分别催化宿主DNA的甲基化和非甲基化DNA的水解；催化非甲基化DNA的水解；或者行使修饰及认知切割的作用。

参考文献

[1]. Loenen WA, et al. Highlights of the DNA cutters: a short history of the restriction enzymes. Nucleic Acids Res. 2014 Jan;42(1):3-19.