Ribosomal protein S6 (RPS6)

核糖体蛋白 S6

英文解释

Ribosomal protein S6 (RPS6) is a component of the 40S small ribosomal subunit and participates in the control of mRNA translation. Phospho (p)-RPS6 is a surrogate marker for the activated PI3K/AKT/mTORC1 pathway, which occurs in many cancer types.

中文解释

核糖体蛋白 S6 (RPS6) 是 40S 小核糖体亚基的组成部分，参与 mRNA 翻译的控制。磷酸化的 RPS6 是激活的 PI3K/AKT/mTORC1 通路的替代标志物，该通路存在于许多癌症类型中。

参考文献

[1]. Yong Weon Yi, et al. Ribosomal Protein S6: A Potential Therapeutic Target against Cancer? Int J Mol Sci. 2021 Dec 21;23(1):48.