Runt-related transcription factor 2 (RUNX2)

Runt-相关转录因子-2

英文解释

Runt-related transcription factor-2 (Runx2) is an essential transcription factor for osteoblast differentiation. Runx2 is a regulator of vascular smooth muscle cell osteogenic transition, a key component of vascular calcification.

中文解释

Runt-相关转录因子-2 (RUNX2) 是成骨细胞分化的重要转录因子。Runx2 是血管平滑肌细胞发生成骨转化的调节剂，是血管钙化的关键组成部分。

参考文献

[1]. Cobb AM, et al. Runx2 (Runt-Related Transcription Factor 2) Links the DNA Damage Response to Osteogenic Reprogramming and Apoptosis of Vascular Smooth Muscle Cells. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1339-1357.