Single nucleotide polymorphisms (SNPs)

单核苷酸多态性

英文解释

Single nucleotide polymorphisms (SNPS) are the basis of genetic diversity and constitute biodiversity together with species diversity and ecosystem diversity. Single nucleotide polymorphism (SNPS) refers to the diversity of DNA sequences caused by the variation of a single nucleotide at the genome level. Its main forms are insertion, deletion, mutation and replacement, which are closely related to multifactorial diseases.

中文解释

单核苷酸多态性 (SNPs) 是遗传多样性的基础，与物种多样性和生态系统多样性共同构成了生物多样性。单核苷酸多态性指的是在基因组水平上由单个核苷酸的变异所引起的DNA 序列多样性，其数量很多，多态性丰富。它的主要形式为插入、缺失、突变和替换，与多因子疾病密切相关。

参考文献

[1]. Ramírez-Bello J, et al. Implicaciones funcionales de los polimorfismos de un solo nucleótido (SNP) en genes codificantes de proteínas y no codificantes en enfermedades multifactoriales
[Functional implications of single nucleotide polymorphisms (SNPs) in protein-coding and non-coding RNA genes in multifactorial diseases]. Gac Med Mex. 2017 Mar-Apr;153(2):238-250. Spanish.