Squalene monooxygenase (SQLE)

角鲨烯单加氧酶

英文解释

Squalene monooxygenase (SQLE)?is an enzyme that catalyzes the stereospecific conversion of squalene to 2,3(S)-oxidosqualene, a key step in cholesterol biosynthesis.

中文解释

角鲨烯单加氧酶 (SQLE) 是一种催化角鲨烯立体定向转化为 2,3(S)-氧化角鲨烯的酶，是胆固醇生物合成的关键步骤。

参考文献

[1]. Padyana AK,et al. Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase. Nat Commun. 2019 Jan 9;10(1):97.5.