Structure–activity relationship (SAR)

构效关系

英文解释

Structure-activity relationship (SAR) is a method used in the detection of the chemical and biological activity relationship of compounds. SAR can be helpful in improving potency, reducing toxicity, and ensuring sufficient bioavailability.

中文解释

构效关系 (SAR) 是一种用于检测化合物化学和生物活性关系的方法。SAR 有助于提高药物效力，降低毒性并确保足够的生物利用度相关的研究。

参考文献

[1]. Guha R. On exploring structure-activity relationships. Methods Mol Biol. 2013;993:81-94.