Survivin (BIRC5)

生存素

英文解释

Survivin (BIRC5) is known as a dual cellular functions protein that directly regulates both apoptosis and mitosis in embryonic cells during embryogenesis and in cancer cells during tumorigenesis and tumor metastasis.

中文解释

生存素 (BIRC5) 是一种双细胞功能蛋白，在胚胎发生过程中直接调控胚胎细胞的凋亡和有丝分裂，在肿瘤发生和肿瘤转移过程中直接调控癌细胞的凋亡和有丝分裂。

参考文献

[1]. Lin TY, et al. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Autophagy. 2020 Jul;16(7):1296-1313.