Tetrahydrofolate (THF)

四氢叶酸

英文解释

Tetrahydrofolate (THF) is a folic acid derivative, exhibits a high antioxidant activity in oxidative stress. Tetrahydrofolate (THF) mitigates the inhibitory effect of oxidative stress on neural stem cell (NSC) proliferation via PTEN/Akt/mTOR signaling pathway.

中文解释

四氢叶酸 (THF)，是一种叶酸衍生物，在氧化应激中表现出较高的抗氧化活性。四氢叶酸通过 PTEN/Akt/mTOR 信号通路缓解氧化应激对神经干细胞 (NSC) 增殖的抑制作用。

参考文献

[1]. Zhang X, et al. Tetrahydrofolate Alleviates the Inhibitory Effect of Oxidative Stress on Neural Stem Cell Proliferation through PTEN/Akt/mTOR Pathway. Oxid Med Cell Longev. 2022 Feb 27;2022:9021474.