Transforming growth factor-β (TGF-β)

转化生长因子-β

英文解释

Transforming growth factor-β (TGF-β) is the largest family of secreted growth factors composed of several subfamilies, including TGF-βs, BMPs, GDFs, activins, inhibins, and GDNFs. TGF-β regulates various biological processes including cell proliferation, differentiation, migration, adhesion, apoptosis and extracellular matrix (ECM) production.

中文解释

转化生长因子-β (TGF-β) 是最大的分泌生长因子家族，由几个亚家族组成，包括 TGF-β、BMP、GDF、激活素、抑制素和 GDNFs。 TGF-β 调节各种生物过程，包括细胞增殖、分化、迁移、粘附、凋亡和细胞外基质 (ECM) 的产生。

参考文献

[1]. Kubiczkova L, et al . TGF-β - an excellent servant but a bad master. J Transl Med. 2012 Sep 3;10:183.