Translocated promoter region (TPR)

易位启动子区

英文解释

Translocated promoter region (TPR) is a prominent architectural component of the nuclear pore complex that forms the basket-like structure on the nucleoplasmic side of the pore. TPR stands for translocated promoter region, which implicates in a variety of nuclear functions, including nuclear transport, chromatin organization, regulation of transcription, and mitosis.

中文解释

易位启动子区 (TPR) 是核孔复合体的重要结构组成部分，在孔的核质侧形成篮状结构。TPR 代表易位启动子区域，它涉及多种核功能，包括核转运、染色质组织、转录调节和有丝分裂。

参考文献

[1]. Chelsi J Snow, et al. Roles of the nucleoporin Tpr in cancer and aging. Adv Exp Med Biol. 2014;773:309-22.