Ubiquitin

泛素

英文解释

Ubiquitin is a small protein, consisting of 76 amino acids, found in most eukaryotes. Its main function is to mark proteins that need to be broken down for degradation by the 26S proteasome.Protein ubiquitination and deubiquitination control the initiation, execution, and termination of bulk autophagy as well as ubiquitination involves in signaling certain types of selective autophagy.

中文解释

泛素是一种小蛋白质，由76个氨基酸组成，存在于大多数真核生物中。它的主要功能是标记需要被26S蛋白酶体分解降解的蛋白质。蛋白质泛素化和去泛素化控制了大量自噬的起始、执行和终止，泛素化还涉及到某些类型的选择性自噬信号。

参考文献

[1]. Chen RH, et al. Ubiquitin-mediated regulation of autophagy. J Biomed Sci. 2019 Oct 21;26(1):80.