- 客服:
- 电话: 13061953619
- 微信:
MYCi975 (NUCC-0200975) is a potent, selective and orally active inhibitor of MYC that disrupts MYC/MAX interaction, promotes MYC T58 phosphorylation and MYC degradation, and impairs MYC driven gene expression. MYCi975 exhibits potent anti-tumor activities
MYCi975 (NUCC-0200975) is a potent, selective and orally active inhibitor of MYC that disrupts MYC/MAX interaction, promotes MYC T58 phosphorylation and MYC degradation, and impairs MYC driven gene expression. MYCi975 exhibits potent anti-tumor activities.
[1] Huiying Han, et al. Cancer Cell. 2019 Nov 11;36(5):483-497.e15. [2] Hikita T, et al. Cancer Sci. 2022 Apr;113(4):1264-1276. [3] Liu S, et al. Oncoimmunology. 2022 Sep 30;11(1):2130583.
动态评分
0.0