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A fluorogenic substrate for caspase-6
Z-VEID-AFC is a fluorogenic substrate for caspase-6. Upon enzymatic cleavage by caspase-6, 7-amino-4-trifluoromethylcoumarin (AFC) is released and its fluorescence can be used to quantify caspase-6 activity. AFC displays excitation/emission maxima of 400/505 nm, respectively.
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